Department of Mathematics

CoSy Lunch Seminar

  • Date: 11/28/2017 at 12:15 PM 1:00 PM
  • Location: Ångströmlaboratoriet, Lägerhyddsvägen 1 Å4003
  • Lecturer: Yevgen Ryeznik, Department of Mathematics, Uppsala University
  • Organizer: CIM
  • Contact person: Joel Dahne
  • Phone: 0762020507
  • Seminarium

Optimal Designs and Adaptive Randomization Techniques in Clinical Trials; Speaker: Yevgen Ryeznik, Department of Mathematics, Uppsala University

28 November
Speaker: Yevgen Ryeznik, Department of Mathematics, Uppsala University
Title: Optimal Designs and Adaptive Randomization Techniques in Clinical Trials
Place: Å4003
Time: 12:15 -- 13:00
Abstract:
Clinical trials are prospective biomedical or behavioral research studies on human subjects that are designed to answer specific questions about biomedical or behavioral interventions. The standard approach of performing such studies is based on the equal allocation of involved subjects between treatment arms. However, it might be that this approach is a nonoptimal choice. In this case, an optimal design and a well-chosen randomization procedure can improve the trial's efficiency. In my talk, I will give a brief overview of the state of the art of the optimal strategies that could be used in real clinical trials.